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Direct reaction of GSH and Cys with Q The solution of Q (0.1 mmol in 10 mL ACN) was added dropwise to the solution of GSH (0.2 mmol in 10 mL saturated sodium bicarbonate)

2b), confirmed the specific sequence of hsa-let-7c (UGAGGUAGUAGGUUGUAUGGUU), and thus acquired the real-time sequence (Table 1)