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Improves brain focus: Enhanced synaptic transmission and neuroplasticity support sustained attention and mental clarity

Turning on cGMP-dependent pathways to treat cardiac dysfunctions: boom, bust, and beyond Trends Pharmacol Sci 35 8: 404-13

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Immunosuppressive therapy: Depending on the severity of the irAE, immunosuppressive medications, such as corticosteroids (e.g., prednisone) or other immunomodulatory agents (e.g., infliximab, mycophenolate mofetil), may be used to suppress the overactive immune response and control inflammation

Notably, several drugs targeting the ERK pathway have been shown to have desirable therapeutic effects in alleviating ferroptosis