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These findings suggest that microbiome-related metabolites may serve as accessible biomarkers for NIU diagnosis and stratification, although further validation in larger cohorts is needed

This reduced space leaves minimal room for the ligament to move, potentially increasing the risk of wear and tear and raising the likelihood of rupture or partial tears in the ACL

Secreted frizzled-related proteins (SFRPs) are antagonists of this pathway that bind Wnts, downregulate their ability to bind and activate FZD receptors, and inhibit this pathway (73)

Clarifying the functions of TXNIP may be crucial for elucidating the anti-cancer mechanisms of BET inhibitors

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