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Policy and regulatory shortcomings Global regulatory frameworks for wastewater reuse exhibit pronounced regional variability, reflecting divergent governance structures and economic priorities, with policy design functioning simultaneously as both an enabler and a constraint to circularity adoption

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2 Types and sources of environmental endocrine disruptors Environmental endocrine disruptors represent a heterogeneous collection of chemical substances that fundamentally alter hormone signaling pathways, thereby compromising endocrine homeostasis and reproductive function