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Vitamin B12 belongs to the water-soluble B-complex group but exhibits unusual storage capacity, with the liver holding 25 mg for 35 years

2.3 Genetic susceptibility: shared genetic architecture EDC exhibits significant genetic susceptibility, with its comorbidity risk potentially influenced by shared genetic variants

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Campion SN, Johnson R, Aleksunes LM, Goedken MJ, van Rooijen N, Scheffer GL, Cherrington NJ, Manautou JE

In summary, although evidence for single intervention strategies varies, given the complexity of CP/CPPS pathology, the most feasible future direction lies in constructing multi-target combination intervention regimens covering anti-inflammation + antioxidation + endocrine correction + microecological regulation based on patient phenotypic stratification, with the aim of achieving the dual goals of symptom relief and fertility protection ( Table 1 )