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a , Total GPX4 activity of HT1080 cells overexpressing GFP-GPX4 WT , GFP-GPX4 K48A , or GFP-GPX4 K48L and a control line

Bax and Bak promote apoptosis by modulating endoplasmic reticular and mitochondrial Ca2+ stores

HDAC inhibition increases acetylation of the NR3C1 gene (encoding the glucocorticoid receptor), enhancing glucocorticoid receptor sensitivity and restoring the negative feedback of the hypothalamic-pituitary-adrenal (HPA) axis