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Here, we identify a high level of genetic correlation between ASXL1 and the major transcriptional activator BRD4 in cancer cells and characterize the molecular mechanism underlying this correlation

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It will be fascinating to explore the in vivo crosstalk of those key redox couples further in the future, and to understand situations in which the glutathione and NADP redox couples are clearly not coupled, including those documented in this manuscript

McKenna MJ, Medved I, et al

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