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For example, certain flavonoids have been demonstrated not only to inhibit the transcription of inflammatory factors but also to enhance cellular antioxidant defenses by modulating redox-sensitive proteins and improve mitochondrial metabolic function

Intranasal deferoxamine reverses iron-induced memory deficits and inhibits amyloidogenic APP processing in a transgenic Alzheimers disease mouse model

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Pharmacokinetic simulation and area under the curve estimation of drugs subject to enterohepatic circulation

thus, the biosynthesis of aspartate and downstream metabolites is intimately tied to mitochondrial activity