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Additionally, to balance the blood capacity taken and the sampling of terminal elimination, samples were collected at 2 h, 4 h, 8 h (Group A, 33 patients) and 2 h, 6 h, 12 h (Group B, 32 patients) after the infusion of dose12 (Figure 1)

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The continuous dose of 2 mg/kg/day for 28 days is consistent with sub-chronic exposure models designed to evaluate oxidative stress and inflammation [25, 26]

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Mol Cell 84, 802810 e806 (2024)