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The failure of these pumps leads to an imbalance of ions across the cell membrane, with an influx of sodium and calcium into the cell and an efflux of potassium (de Lores Arnaiz, 2007

right: quantification of sarcomere density based on IF staining for sarcomeric actinin, comparing Ctrl Cre and Cpt1b cKO adult CMs (n = 3, each)

Electron microscopy A screening dataset was recorded on a Glacios cryo-transmission electron microscope at 200 kV using a Gatan Vista Alpine detector in counting mode and SerialEM software (v.4.1)