glutathione effect on ovarian cancer

glutathione effect on ovarian cancer Transferase P1: Potential Therapeutic Target in Cysteine allows ovarian cancer cells

Name: glutathione effect on ovarian cancer Transferase P1: Potential Therapeutic Target in Cysteine allows ovarian cancer cells
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Cysteine allows ovarian cancer cells to adapt to hypoxia and to escape from carboplatin cytotoxicity Scientific Reports Carbon monoxide sensitizes cisplatin resistant ovarian cancer cell lines toward cisplatin via attenuation of levels of glutathione and nuclear metallothionein ScienceDirect Frontiers Unveiling drug resistance pathways in high grade serous ovarian cancer(HGSOC): recent advances and future perspectives Targeting ferroptosis in ovarian cancer: Novel strategies to overcome chemotherapy resistance ScienceDirect Glutathione Reduces Cisplatin Side Effects in Ovarian Cancer evercare

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doi: 10.1016/j.prp.2024.155617 10 HuangZMaYSunZChengLWangG

The reasons therefore can most probably be found in a high degradative activity of GGT1 and GGT2 which degrade glutathione and are located in the cell wall and the plasma membrane, respectively