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Maddie McAshlin

In animal reproduction studies, no fetotoxicity was observed when nitrofurantoin was administered orally to pregnant rats and rabbits, during organogenesis, at up to 6 times the recommended human dose (see Data)

Pataer A, Vorburger SA, Chada S, Balachandran S, Barber GN, Roth JA, Hunt KK, Swisher SG

37 JenaM

Elevated excretion of p -cresol sulfate was accompanied by a reduced production of N-acetylcysteinyl conjugates of acetaminophen suggesting an impaired ability to detoxify APAP reactive metabolites