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Fardella, W.L

The elucidation of different mechanisms of disease progression facilitates the development of targeted therapies, while the intrinsic linkages in disease mechanisms are equally noteworthy, as their interactions pose serious challenges for clinical treatment

They follow disc injury in animal models 22 , although the small and young animals used in such experiments are not always a reliable guide to disc degeneration in humans 22,23 , for whom no equivalent data are available

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Capsule endoscopy has a significantly higher diagnostic yield in patients with suspected and established small-bowel Crohns disease: a meta-analysis