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Stimulates fibroblasts to produce type I and III collagen, glycosaminoglycans, and decorin rebuilding the extracellular matrix architecture in damaged tissue

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In contrast, a correlation between the total nerve number and the tyrosine hydroxylase-positive nerve (sympathetic nerve) number was not observed, which confirmed that the loss of nNOS-positive minor branches of the DPNs was representative morphological evidence of the rat BCNI model, primarily observed by light microscope (Fig

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Circulation 124:17651773 Willmann JK, Chen K, Wang H, Paulmurugan R, Rollins M, Cai W, Wang DS, Chen IY, Gheysens O, Rodriguez-Porcel M et al (2008) Monitoring of the biological response to murine hindlimb ischemia with 64Cu-labeled vascular endothelial growth factor-121 positron emission tomography