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gingivalis , Actinomyces , and Fusobacterium nucleatum , resulting in the production of high levels of short-chain fatty acids (SCFAs), such as lactate, acetate, and butyrate, which are correlated with periodontitis severity [67]

Since vitamin B12 deficiency is associated with abnormal TNF- activity, it can also lead to insulin resistance (88, 89)

A score of 34 points was considered mild symptoms, 56 points as moderate symptoms, and 79 points as severe symptoms

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