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[31] used H 2 O 2 and azalea alcohol to induce oxidative stress in normal human primary melanocytes as a model, demonstrating that 6-shogaol can alleviate the damage of H 2 O 2 and azalea alcohol to human primary melanocytes by upregulating the expression of antioxidant enzymes heme oxygenase-1 (HO-1) and quinone oxidoreductase-1 (Nqo1), activating Nrf2-antioxidant response element (Nrf2-ARE) pathway

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In general, PPT is phosphorylated in GS in the presence of ATP and forms an intermediate state analogue, phosphinothricin phosphate (P3P), and ADP 24,25

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