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10.1186/s13020-017-0140-2 118 ZhangZ

Intense pulsed light (IPL), Low-fluence Q-switched (LFQS) lasers, non-ablative fractional lasers (NAFL), and picosecond lasers are among the most frequently used light and laser-based therapies in melasma management (Goel et al., 2011)

private clinic study]

This entire process is highly dependent on cellular energy, requiring adenosine triphosphate (ATP) to function correctly

As a prevailing pitfall, and unsuited over-simplification, such a NO-system complexity in functioning remained hidden in most studies using only one part regularly, mostly the NO-system inhibition as a theoretical background [97]