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#17,000 Nature Renaissance inter

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NA-Cis-AuNRs suppress angiogenic factors in the tumor microenvironment model To further validate the role of angiogenic transcription factors in the above experiment, RNA was isolated from developing CAM blood vessels and analyzed by RT-qPCR to assess the expression of key angiogenic transcription factors, suggesting their role in promoting the proliferation of endothelial cells and the formation of capillary-like structures

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Then, the pyrimidine ring and 5-pyriphosphoribosyl pyrophosphate (5-PRPP), generated from the pentose phosphate pathway (PPP), are catalyzed to form orotidine 5-monophosphate (OMP) via dihydroorotate dehydrogenase (DHODH)