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Ann N Y Acad Sci 2004;1033:158-67

The DOPE SRO (single-resident occupancy) initiative was created in 2020 and expanded in 2021 to address the rising number of opioid-related overdoses by people who use drugs while using alone in their home

To further substantiate that it is indeed mTORC1 that mediates the positive regulation of ERO1 downstream of the TSC1/TSC2 complex, we detected ERO1 levels in mTOR, Raptor (a specific component of mTORC1) or Rictor (a specific component of mTORC2) knockdown Tsc2 / MEFs

However, their outcomes vary depending on isomer, dosage, baseline status, and population characteristics [2,18,45,46]

Am J Hum Genet 1996