Shaking creates mechanical stress and shearing forces that can break the fragile peptide bonds, rendering it useless
Monserrat-Mesquida M, Quetglas-Llabrs M, Abbate M et al (2020) Oxidative stress and pro-inflammatory status in patients with non-alcoholic fatty liver disease
To further complicate matters, the study states: "no clear optimal [pH range] was seen when the test was run without [fatty acid byproduct]." It was only used to compare how animal and human skin metabolises the form of vitamin A naturally present in the skin, not about how topical vitamin A (retinol) benefits the skin
These systems also protect fragile antigenic materials from enzymatic breakdown within the body, ensuring that the immune system encounters them in their active form
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