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Vascular Resistance, Flow, and Mean Arterial Pressure murmur (best heard at upper sternal borders) Jaundice Jaundice Jaundice is the abnormal yellowing of the skin and/or sclera caused by the accumulation of bilirubin

Wu MH, Lu RY, Yu SJ, Tsai YZ, Lin YC, Bai ZY, et al

Once a lead compound is found, the candidate has to be assessed in the preclinical stage to establish the safety and efficacy, including information about properties such as absorption, distribution, metabolization, and excretion, as well as the best dosage and administration route, and side effects/adverse events

ER stress and dysregulation of the UPR are associated with NAFLD/non-alcoholic steatohepatosis (NASH) in humans (Gonzalez-Rodriguez et al., 2014, Lake et al., 2014, Lebeaupin et al., 2015, Lebeaupin et al., 2018), and in mice on NASH-promoting diets (Charlton et al., 2011, Rahman et al., 2007)

B) Bar graph representing the percent correlation of treatment-induced postsynaptic spines to the glutamatergic presynaptic marker VGLUT1