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Characteristic structural features Each soluble GST is a dimer of approximately 26 kDa subunits, typically forming a hydrophobic 50 kDa protein with an isoelectric point in the pH range 4-5

While impressive, it is important to note that the products effects will vary among individuals

Acetaldehyde-modified proteins have also been detected in the plasma (Liu et al., 1990) and haemoglobin of alcoholics (Niemela & Israel, 1992)

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Implications for drug development The discovery of CD36 as a "universal carrier" suggests that medicinal chemists can rationally enhance CD36 binding to improve intracellular exposure