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doi:10.1159/000322698 Moseley L., Lancaster G.I, Jeukendrup A.E

The comparison between the peptides with analgesic activity and the positive control drug is summarized in Table 7

Fagopyrum esculentum contains amygdalin, rutin, and buckwheat inhibitor-1 protein, which exert anticancer effects against pancreatic cancer and T-acute lymphoblastic leukemia (T-ALL) cells by decreasing the signaling effect of the PI3K/AKT and Bcl-2 pathways and inducing the expression levels of BAX and caspase-3, resulting in cancer cell death [134, 135]