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1, 2 Previous studies have reported that decreased expression of UCP-1 caused by various conditions such as fasting, deletion of the UCP-1 gene, and obesity (eg, ob/ob and db/db mice) induces a low body temperature resulting from the impaired thermogenesis in BAT

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Standard B12 blood tests strip B12 off all its carrier proteins and measure the total freed B12, so they cant distinguish between normal B12 and macro-B12: both contribute equally to the reading