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In a recent study, male sex, age, family history of PHG, and obesity were all factors significantly associated with premature graying

Olesen MN et al

*Correspondence: Neda Roshanravan, [email protected] Dehghan, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

In the early stage of sepsis, pathogen stimulation drives macrophages to polarize towards the pro-inflammatory M1 phenotype, secreting cytokines such as TNF- and IL-1, which disrupt the alveolar-capillary barrier

Exercise training can reduce age-related apoptosis of cardiac cells by lowering the proportion of pro-apoptotic protein Bax in relation to anti-apoptotic protein Bcl-2 in cardiac cells, thereby slowing down cardiac remodeling and functional decline