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Tenuigenin protects cultured hippocampal neurons against methylglyoxal-induced neurotoxicity

Further research by Wei et al (103) and Yu et al (104) revealed that glycolysis inhibition using dichloroacetate (DCA) (103) or 3-bromopyruvate (104) could reduce renal fibrosis

Irvine, S

The NRF2 further activates antioxidant enzymes to terminate macrophages-initiated pathological cascades and reestablish intra-articular immune homeostasis, conferring a bone recovery and chondroprotective effect in collagen-induced arthritis mouse models

Oxidative Stress Explained Oxidative stress is when reactive oxygen species (ROS) and other free radicals overwhelm the antioxidant defenses that neutralize them