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Phosphoproteome profiling of AD models highlights alterations independent of protein levels Since protein phosphorylation is known to contribute to AD pathogenesis 53,54 , we profiled the phosphoproteome in the same set of NLGF (3-, 6-, 12-, 18-month-old) mice and 5xFAD (12-month-old) and their age-matched WT controls

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When vitamin B12 levels are too low, the production of red blood cells is altered, causing megaloblastic anemia

These results suggest that TLYY may alleviate UC by promoting beneficial bacteria and enhancing SCFA production

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