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Glutathione plays a role in protecting neurons from oxidative damage, supporting cognitive clarity, and maintaining vascular function through improved endothelial health

It has been established that intramitochondrial Ca 2+ triggers a cascade of processes within the mitochondrion that increase ATP synthesis through oxidative phosphorylation, the activation of three dehydrogenases in the tricarboxylic acid (TCA) cycle, which facilitates increased generation of NADH and consequently the transfer of electrons to an acceptor such as O 2 (Gunter et al., 2004[178])

Wake H, Moorhouse AJ, Jinno S, Kohsaka S, Nabekura J (2009) Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals

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The finding that senescent cell clearance in the testes can partially restore testosterone production suggests a novel mechanism for addressing late-onset hypogonadism