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ROS activate the NLRP3 inflammasome, which in turn stimulates IL-1 maturation and neutrophil recruitment, in addition to NF- and AP-1, which produce pro-inflammatory cytokines and adhesion molecules

da Silva TU, Pougy KC, Albuquerque MG, da Silva Lima CH, Machado SP (2022) Development of parameters compatible with the CHARMM36 force field for [Fe 4 S 4 ] 2+ clusters and molecular dynamics simulations of adenosine-5-phosphosulfate reductase in GROMACS 2019

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For my watch the uncertainty is in the milliseconds

Visser and A.G.J