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Am J Clin Nutr 2006;83(6 suppl):1505S19S

Resveratrol can also inhibit the phosphorylation and activation of vascular endothelial growth factor receptor 2 in endothelial cells and exert anti-AMD effects by activating SIRT1, as well as down-regulating the expression level of hypoxia-inducible factor-1 (HIF-1) and VEGF secretion in RPE cells (Zhang et al., 2015)