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SKU: 13659024557
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Description

The excessive accumulation of ROS induces oxidative stress and subsequently leads to cell death

Soc Trans

Hepatology 21:1045-1050 Latchoumycandane C, Seah QM, Tan RC, Sattabongkot J, Beerheide W, Boelsterli UA (2006) Leflunomide or A77 1726 protect from acetaminophen-induced cell injury through inhibition of JNK-mediated mitochondrial permeability transition in immortalized human hepatocytes

Therapeutic or experimental strategies targeting aging organize around three main axes: senolytics (selective elimination of senescent cells), senomorphics (SASP modulation without killing cells), and geroprotectors (reinforcement of anti-aging mechanisms like autophagy, mitophagy, telomerase activity)