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Description

Inskeep PB, Koga N, Cmarik JL, & Guengerich FP (1986) Covalent binding of 1,2-dihaloalkanes to DNA and stability of the major DNA adduct, S-[2-(N7-guanyl)ethyl]glutathione1

Hirsch et al

LIAS binds two [4Fe-4S] clustersthe first mediates a radical SAM reaction that activates the aliphatic chain for sulfur attachment, while the second acts as a sulfur donor and must be replenished after each reaction 58