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When used appropriately under medical supervision, B12 injections are generally considered very safe

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Smith, Mary C., and David M

For example, individuals with gastrointestinal issues may find injections more beneficial, as they ensure the vitamin bypasses the digestive system entirely

Adequate maternal folate status protects against neural tube defects and supports proper brain development, while deficiency is associated with persistent alterations in offspring neurodevelopment and an increased risk of obesity and insulin resistance later in life [112,113,114]