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Upon catalysis of COXs, dihomo--linolenic acid (DGLA) and arachidonic acid (AA) can be oxidized by radical-mediated lipid peroxidation and produce prostaglandins, which linking the lipid peroxidation directly to inflammation and apoptotic processes [32,33,34]

10.1016/j.radonc.2014.02.010 Radiother

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Surtout si la production corporelle est inhibe par des troubles mtaboliques (p

Polyunsaturated fatty acids (PUFAs) have been shown to reduce hepatic triglyceride accumulation, while diets high in the n-6/n-3 PUFA ratio and low in total PUFA content are linked to the development of fatty liver and other chronic metabolic disorders [75, 76]