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Supporting this, increased nitrotyrosine staining, an indicator of peroxynitrite-mediated protein damage, has been detected in sputum macrophages from COPD patients and correlates with worsened lung function [87]

2002 May-Jun;9(3):225-33

5.5 Therapeutic approaches targeting ferroptosis in melanoma Recent research advancements have significantly illuminated the pivotal role of ferroptosis in the pathogenesis and treatment strategies of melanoma (206, 207)