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[55] [56] Interaction with tumour suppressor genes PTEN PTEN (phosphatase and tensin homolog) is a tumor suppressor gene encoding a protein PTEN, which possesses lipid and protein phosphatase-dependent as well as phosphatase-independent activities

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10.1016/j.tox.2006.06.008 38

Suitable for further studies (Phase 3) in patients with obesity

Our poor understanding of the mechanisms governing T production limits the design of agonistic therapeutics, despite the pressing need to treat patients affected by reduced serum T levels