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Simultaneous depletion of GSH and glucose leads to increased susceptibility of tumor cells to GOx@[Cu(tz)]-mediated cuproptosis, resulting in significant oligomerization of DLAT proteins

They catalyze the nucleophilic attack of reduced glutathione (GSH) on the electrophilic centers of these molecules

2.1.2 Acetylcholinesterase Acetylcholinesterase (AChE, EC 3.1.1.7), also known as choline esterase I, cholinesterase, or true cholinesterase ( Torpedo californica , featuring 14 -helices surrounding a 12-stranded mixed -sheet with an active site comprising a planar array formed by three residues in loops within highly conserved regions (Sussman et al., 1991

Herein, we systematically explore the well-documented ESCMs extracts or constituents with explicit anti-cancer properties, alongside their underlying mechanisms and pathways

At the mRNA level, biogas slurry treatment reconstructs carbon and nitrogen metabolic fluxes by activating genes related to the cell cycle while concurrently downregulating genes involved in carbon fixation