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Historically, a flow-limiting epicardial stenosis was viewed as an indication for mechanical revascularization to prevent myocardial infarction and prolong life

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Data availability Raw data were generated at Neuroscience Institute Cavalieri Ottolenghi, Department of Neuroscience Rita Levi Montalcini, University of Turin, Turin, Italy and Institute of Biosciences and BioResources (IBBR), National Research Council (CNR), Naples, Italy