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Int J Biol Sci 7:823836 Gomez KA, Gomez AA (1984) Statistical procedures for agricultural research

Preclinical models show NNMT inhibition can reduce white adipose tissue accumulation and, in some studies, reverse diet-induced obesity in animal subjects

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Consistently with a role in fibroblast activation, an amelioration of tissue fibrosis was observed in TLR4 knockout in murine models of systemic sclerosis [131]