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J Clin Investig 117:16581669 Hillson JL, Furst DE (1997) Pharmacology and pharmacokinetics of methotrexate in rheumatic disease: practical issues in treatment and design

GSH in the ACC was positively correlated with circulating concentrations of TIMP-2 ( R = 0.539, p = 0.008)

Polyphenols could neutralize the free radicals of both reactive oxygen species (ROS) and reactive nitrogen species (RNS), which can damage the chromosomes and consequently modify the encoded amino acid and the associated biological process (163)