glutathione copper

glutathione copper Engineering Dual-Responsive Nanoplatform Achieves Metabolism Disruption and Consumption to Provoke Cuproptosis/Ferroptosis/Apoptosis for Cancer Therapy Evolution of copper, zinc, selenium

Name: glutathione copper Engineering Dual-Responsive Nanoplatform Achieves Metabolism Disruption and Consumption to Provoke Cuproptosis/Ferroptosis/Apoptosis for Cancer Therapy Evolution of copper, zinc, selenium
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Description

The relationship between DSIP dose and effect in humans has never been mapped

Fallopia (or Poligonum cuspidatum) is a plant high in Resveratrol

However, combined exposure resulted in unexpectedly lower toxicity than either pollutant alone

By integrating cryo-electron microscopy (cryo-EM), ubiquitin absolute quantification mass spectrometry (Ub-AQUA), and cross-linking mass spectrometry (XL-MS), the team has successfully determined a high-resolution structure of the human proteasome bound to a branched K11/K48-linked ubiquitin chain