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Role of endoplasmic reticulum stress in nano-selenium alleviating prehierarchical follicular atresia induced by mercury in laying hens

Ethics statement The animal studies were approved by Institutional Animal Care and Use Committee (IACUC) National Taiwan University

Figure 3 Collectively, our findings suggest a role for NLRP3-mediated ASC-speck formation and caspase-1 activation in pathologic inflammation associated with moderate and severe forms of COVID-19 supporting potential use of NLRP3 inhibition to mitigate the exacerbated inflammasome-related responses during COVID-19

Reactions were terminated by heating at 98 C for 2 min to inactivate Proteinase K, followed by reduction with 10 mM dithiothreitol at 37 C for 30 min and alkylation with 40 mM iodoacetamide at 37 C for 45 min in the dark