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Overall, these results highlight the regulation of G6PD protein during the infection by NRF2 and underscore the interrelationship between glucose metabolism and susceptibility to viral infections during glucose metabolic alterations, supporting the central role of G6PD pathway modulation

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The gill tissue samples included one piece of gill from the same position on the same side of each fish and were stored at 20 C to determine biochemical indices and 80 C to determine molecular indices

IGF-1 regulates dopamine release from these neurons, and the absence of IGF-1 in dopaminergic neurons decreases dopamine levels in the striatum, leading to deficits in dopamine neuron firing, spontaneous locomotion, and exploratory and learning behaviors (53)

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