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Unlike growth hormone itself, IGF-1 works directly at the cellular level to promote tissue growth and repair

however, only K4 and SPH domains of HGF II were resolved, suggesting that the first four domains of HGF II are less tightly bound at the receptor and thus become flexible (Supplementary Fig

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Also described herein are formulations or compositions that are stable with respect to pH over a period of at least about 1 month

This docking-guided framework provided mechanistic hypotheses for THCs pleiotropic effects and prioritized key targets for translational development