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Basic Clin Pharmacol Toxicol 100:308315 Fisher AEO, Naughton DP (2003) Redox-active metal ions and oxidative stress: therapeutic implications

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Prior to docking, the receptor protein was further processed in PyMOL 2.5.2 to remove residual water molecules, salt ions, and small molecules

Since mitochondria are one of the crucial organelles involved in the manifestation of radiation-induced apoptosis, Stoyanovsky and coworkers anticipated that mitochondrial targeting of ebselen may further improve its radioprotective activity by detoxifying the mitochondrial overproduction of hydroperoxide (H 2 O 2 ) and the accumulation of lipid hydroperoxides

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