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Some cases of covert hepatic encephalopathy were difficult to evaluate and diagnose, because of lacking reliable diagnostic clinical signs

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Gene therapy approaches, including AAV-mediated enhancement of the endogenous SCN1A promoter and CRISPR/dCas9-driven transcriptional activation, selectively augment Nav1.1 sodium channel expression in inhibitory interneurons

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Archived from the original on 13 October 2014