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Preclinical studies have not identified major safety concerns under experimental conditions, but: comprehensive human safety data are not yet available

10.1016/j.survophthal.2021.07.008 Terluk MR, Ebeling MC, Fisher CR, et al.: N-Acetyl-L-cysteine Protects Human Retinal Pigment Epithelial Cells from Oxidative Damage: Implications for Age-Related Macular Degeneration