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4.2 Circadian rhythm disruptions and common eye diseases Circadian rhythm disruptions are closely associated with the development and progression of several ocular diseases, including DED (Zeng et al., 2024), glaucoma (Turner et al., 2010), and retinal diseases (McMahon et al., 2014)

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Although several studies have supported the view that CX36 may also be involved in epileptogenesis, there is still an ongoing controversy associated with the alterations of CX36 at different developmental stages of human and animal models of epileptogenesis (Wu et al., 2018)

Banwell explains, "Over the past two decades we've seen a 30 per cent increase in lower limbs' amputation rates

This response is independent of driver oncogene and environmental conditions but specific to cancer cells, both in vitro and in vivo, further highlighting the inherent mitochondrial plasticity in cancer