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The possibility of providing treatment options in normal clinical practice rests on two conditions being met: 1) that quality scientific information supports the effectiveness of the therapeutic options on offer, and 2) that heterogeneous groups of patients have recorded their satisfaction with these options

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[7] [9] Use is also contraindicated in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency, as high doses of ascorbic acid may induce hemolysis in this population

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