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Full intracellular retention of GLUT4 requires AS160 Rab GTPase activating protein

Innovative drug delivery systems are being developed to improve the bioavailability and tumor targeting of GPX4 inhibitors like RSL3 and FIN56, while minimizing off-target effects on normal tissues

Lavery, D

Garca JA, Volt H, Venegas C et al (2015) Disruption of the NF-B/NLRP3 connection by melatonin requires retinoid-related orphan receptor-a and blocks the septic response in mice

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